Antiaging composition comprising cytochalasin d or sag, and method for screening antiaging substance
AssigneeAmorepacific Corporation
InventorsHyun Jung CHOI, Hyoung June KIM, Ji Yong JUNG, Tae Ryong LEE
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Abstract
The present disclosure relates to an antiaging composition containing cytochalasin D or SAG, and a method for screening an antiaging substance, and provides a new antiaging substance and a new method for discovering a new antiaging substance. Thus, it is possible to greatly contribute to the development of beauty industries and to meeting demands related with beauty and antiaging, if the present disclosure is effectively used.
Claims27
A method for skin antiaging of a subject, the method comprising:
- administering cytochalasin D, 3-chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]benzo[b]thiophene-2-carboxamide, an optical isomer or stereoisomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof to the subject as a substance increasing the expression of primary cilia.
A method for screening a substance with skin antiaging effect, comprising:
- a step of treating skin cells with a test substance;
- and
- a step of identifying the relative degree of formation of primary cilia in the skin cells before and after the treatment with the test substance.
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A method for diagnosis of skin condition, comprising a step of identifying the degree of formation of primary cilia.
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Dependencies are inferred from the claim text.