Methods and compositions for treating cancer using exosomes-associated gene editing
AssigneeBoard of Regents, The University of Texas System
InventorsRaghu Kalluri, Valerie LeBleu, Fei Xiao
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Abstract
Provided herein are compositions comprising exosomes comprising CD47 on their surface, and further comprising a CRISPR system. Further provided are methods of using the exosomes for gene editing and the treatment of cancer by gene editing.
Claims93
A composition comprising exosomes, wherein the exosomes comprise CD47 on their surface and wherein the exosomes comprise a CRISPR system.
A composition comprising exosomes for use in the treatment of a disease in a patient, wherein the exosomes comprise CD47 on their surface and wherein the exosomes comprises a CRISPR system.
Use of exosomes in the manufacture of a medicament for the treatment of a disease, wherein the exosomes comprise CD47 on their surface and wherein the exosomes comprise a CRISPR system.
Dependencies are inferred from the claim text.