Palonosetron for the treatment or prevention of nausea and vomiting
AssigneeOrion Corporation
InventorsJouko LEVIJOKI, Sari PAPPINEN, Lasse SALORANTA
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Abstract
The invention relates to a method for treating or preventing nausea and vomiting. The method comprises administering an eye drop composition comprising palonosetron or a pharmaceutically acceptable salt thereof to the eye of the subject. The ocular administration results in fast systemic absorption, improved bioavailability compared to oral route and extended elimination time.
Claims23
A method for the treatment or prevention of nausea and vomiting in a subject comprising administering to the eye of the subject in need thereof an effective amount of an eye drop composition comprising palonosetron or a pharmaceutically acceptable salt thereof.
An eye drop composition comprising palonosetron or a pharmaceutically acceptable salt thereof as an active ingredient.
21-24. (canceled)
A medicinal kit comprising a) an eye drop composition comprising palonosetron or a pharmaceutically acceptable salt thereof as an active ingredient, b) a package for containing the composition, and c) instructions for administering the composition on the eye of a patient for the treatment or prevention of nausea and vomiting.
Dependencies are inferred from the claim text.