Dissolvable polymeric eye inserts and method of using same
AssigneeAlcon Inc.
InventorsHoward Allen Ketelson, Rekha Rangarajan, Walter R. Laredo, Stephen John Collins
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Abstract
Polymeric eye inserts are provided that may be dissolvable when placed in the cul-de-sac of the eye. These inserts may contain one or more polymers as well as a softener/plasticizer so that, when inserted into the eye, they may absorb tears, and dissolve and slowly release lubricant into the tear film to lubricate and protect the ocular surface for an extended duration of time. Increased retention time on the ocular surface for longer lasting relief may reduce dosing frequency and patient burden typically associated with topical drop usage. These polymeric eye inserts also may include one or more pharmaceutically active agents.
Claims22
A polymeric eye insert, the insert comprising:
- one or more mucoadhesive polymers that are biocompatible with the ocular surface and tear film of the eye;
- and wherein upon insertion of the polymeric eye insert in the cul-de-sac of the eye, the thickness of the tear film increases for at least 30 minutes post-insertion.
(canceled)
Dependencies are inferred from the claim text.