Ophthalmic composition and delivery device thereof
AssigneeSydnexis, Inc.
InventorsGregory I. OSTROW, Kenneth J. WIDDER, David S. BAKER
Life of this patent
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Abstract
Provided herein is an ophthalmic composition. In some embodiments, the ophthalmic composition includes a low concentration of a muscarinic antagonist or an ophthalmic agent for treatment of an ophthalmic disorder or condition in a preservative-free ophthalmic formulation. Further disclosed herein include an ophthalmic composition including a low concentration of a muscarinic antagonist or an ophthalmic agent and deuterated water. Also disclosed herein are methods of treating an ophthalmic condition or disease by administering to an eye of an individual in need thereof an effective amount of an ophthalmic composition as described herein.
Claims36
An ophthalmic product, comprising:
- a) a fluid-dispensing device comprising a reservoir and a dispensing tip fitted onto the reservoir;
- and
- b) an ophthalmic composition comprising from about 0.001 wt % to about 0.05 wt % of a muscarinic antagonist and deuterated water, at a pD of from about 4.2 to about 7.9, in the reservoir;
- wherein the ophthalmic composition is dispensed from the dispensing tip into an eye of an individual in need thereof, and wherein the dispensed ophthalmic composition is substantially preservative-free.
An ophthalmic product, comprising:
- a) a multi-dose preservative free fluid-dispensing device comprising a reservoir and a dispensing tip fitted onto the reservoir;
- and
- b) an ophthalmic composition comprising from about 0.001 wt % to about 0.05 wt % of a muscarinic antagonist and deuterated water, at a pD of from about 4.2 to about 7.9, in the reservoir;
- wherein the ophthalmic composition is dispensed from the dispensing tip into an eye of an individual in need thereof, and wherein the ophthalmic composition is substantially preservative-free.
A method of delivering an ophthalmic composition to an eye of an individual in need thereof, comprising:
- c) generating at least one droplet containing an ophthalmic composition comprising from about 0.001 wt % to about 0.05 wt % of a muscarinic antagonist and deuterated water, at a pD of from about 4.2 to about 7.9, via a fluid-dispensing device comprising a reservoir and a dispensing tip fitted onto the reservoir;
- and
- d) delivering the at least one droplet containing said ophthalmic composition to the eye of the individual;
- wherein the ophthalmic composition dispensed in step b) is substantially preservative-free.
Dependencies are inferred from the claim text.