Monitor efficacy of laser eye treatment through cell lysis determination
AssigneeXinova, LLC
InventorSeth Adrian MILLER
Life of this patent
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Abstract
Technologies are described for monitoring efficacy of laser treatment through cell lysis determination. Current methods for removing diseased tissue may include directing laser treatment toward cells in a treatment area. The laser treatment may induce lysis of the cells without any visual indication of the lysis occurring. According to some examples, a treatment system may direct a pair of laser pulses to cells in a treatment area. The treatment system may derive a first signal and a second signal based on a detected response to the first and second laser pulse within the pair. A signal processor, according to some examples, may determine a difference between the first signal and the second signal and may modify the laser treatment based on the difference.
Claims30
A method to monitor efficacy of a laser treatment to an eye, the method comprising:
- directing a first laser pulse to a treatment area in the eye;
- detecting a first response from the eye;
- deriving a first signal based on the first response;
- directing a second laser pulse to the treatment area;
- detecting a second response from the eye;
- deriving a second signal based on the second response;
- and
- modifying the laser treatment based on a comparison between the first signal and the second signal.
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A treatment system configured to provide and monitor efficacy of a laser treatment to an eye, the treatment system comprising:
- a laser source configured to sequentially emit a first laser pulse and a second laser pulse at an approximately same intensity to a treatment area in an eye;
- a detector configured to:
- detect a first response from the eye following the emission of the first laser pulse;
- derive a first signal based on the first response;
- detect a second response from the eye following the emission of the second laser pulse;
- and
- derive a second signal based on the second response;
- and
- a processor communicatively coupled to the laser source and the detector and configured to:
- receive the first signal and the second signal from the detector;
- determine a difference between the first signal and the second signal;
- and
- modify the laser treatment based on whether the difference between the first signal and the second signal is above a particular threshold.
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A signal processing apparatus, comprising:
- a communication interface configured to facilitate communication between the signal processing apparatus and a treatment system, wherein the treatment system is configured to direct a first laser pulse to a treatment area in an eye, detect a first response from the eye, derive a first signal based on the first response, direct a second laser pulse to the treatment area, detect a second response from the eye, and derive a second signal based on the second response;
- a processor coupled to the communication interface and the treatment system, wherein the processor is configured to:
- receive, through the communication interface, the first signal and the second signal from the treatment system;
- determine a difference between the first signal and the second signal;
- and
- instruct the treatment system to modify the laser treatment based on a determination whether the difference between the first signal and the second signal is above a particular threshold.
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Dependencies are inferred from the claim text.