Soft, Wearable Microfluidic Systems Capable of Capture, Storage and Sensing of Biofluids
AssigneesThe Board of Trustees of the University of Illinois, Northwestern University
InventorsJohn A. ROGERS, Jungil CHOI, Sungbong KIM
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Abstract
The invention provides systems for handling biofluids including the transport, capture, collection, storage, sensing, and/or evaluation of biofluids released by tissue. Systems of some aspects provide a versatile platform for characterization of a broad range of physical and/or chemical biofluid attributes in real time and over clinically relevant timeframes. Systems of some aspects provide for collection and/or analysis of biofluids from conformal, watertight tissue interfaces over time intervals allowing for quantitative temporal and/or volumetric characterization of biofluid release, such as release rates and release volumes.
Claims19
-100. (canceled)
A device for multiparametric and temporal characterization of sweat comprising:
- a soft and flexible functional substrate for adhering and conforming to a surface of the skin, said functional substrate comprising a microfluidic network channel having a plurality of microchannels and reservoirs configured for time-dependent collection of said sweat;
- and
- a plurality of sensors supported by said functional substrate and configured for multiparametric and temporal analysis of said sweat;
- and
- wherein said microfluidic network channel provides for microfluidic transport of at least a portion of said sweat to said sensors.
A method for analyzing sweat, the method comprising the steps of:
- providing the device of claim 1;
- conformally contacting the functional substrate with a skin surface;
- collecting sweat released from the skin surface in the microfluidic network;
- exposing the plurality of sensors to the collected sweat;
- and
- analyzing the plurality of sweat biomarkers and sweat loss with the plurality of sensors;
- thereby analyzing sweat.
Dependencies are inferred from the claim text.