Methods and compositions for management of gastrointestinal disorders
AssigneeBoard of Regents, The University of Texas System
InventorWilliam T. Phillips
Life of this patent
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Abstract
Described herein are methods of management of functional dyspepsia in a patient by administering an amylin analogue or a CCK composition to the patient. Methods of diagnosing such patient include a standard gastric-emptying assessment using a standardized solid meal along with measurements of blood glucose levels. Another method of diagnosing such patient includes a gastric-emptying scintigraphy assessment with labeled carbohydrates or other assessments to diagnose rapid carbohydrate gastric emptying.
Claims18
A method of treatment of a subject, the method including the steps of:
- classifying a subject as having normal, rapid, or delayed gastric emptying based on a standard gastric-emptying scintigraphy assessment using a standardized solid meal;
- classifying the subject as having elevated, normal, or diminished glycemic excursion based on one or more measurements of blood glucose levels of the subject during the standard gastric-emptying scintigraphy assessment;
- and
- administering an amylin analogue to the subject upon being classified as having delayed gastric emptying and elevated glycemic excursion.
A method of treatment of a subject, the method including the steps of:
- classifying a subject as having normal, rapid, or delayed gastric emptying based on a standard gastric-emptying scintigraphy assessment using a standardized solid meal;
- classifying the subject as having elevated, normal, or diminished glycemic excursion based on one or more measurements of blood glucose levels of the subject during the standard gastric-emptying scintigraphy assessment;
- and
- administering a cholecystokinin composition to the subject upon being classified as having delayed gastric emptying and elevated glycemic excursion.
Dependencies are inferred from the claim text.