Back to results
US 2020/0333024 A1Published application
Compositions and Methods for Treatment of Protease Mediated Disease
AssigneeThe Regents of the University of California
InventorsMichael E. Selsted, Dat Q. Tran
Life of this patent
Estimating the term…
Abstract
A method is provided for a condition related to the activity of a protease through the administration of a θ-defensin, analog, or derivative is described. Suitable proteases include metalloproteases and cysteine proteases such as Cathepsin-C. The θ-defensin, analog, or derivative can be effectively administered parenterally, topically, or orally.
Claims13
A method of treating a condition resulting from activity of a protease in an animal, comprising:
- determining that the animal has the condition related to activity of the protease, and
- administering a pharmacologically acceptable formulation of a θ-defensin to the animal in an amount effective to inhibit the protease.
Dependencies are inferred from the claim text.