Novel compounds which activate estrogen receptors and compositions and methods of using the same

A compound having the formula (iv):

• wherein R1 and R2 is selected from H, C1-4 alkyl group, haloalkyl, hydroxyalkyl, alkyloxyalkyl, cycloalkyloxyalkyl, alkylthio, alkylthioalkyl, cycloalkylthioalkyl, R′R″N-alkyl where R′ and R″ are independently alkyl, alkylcarbonyl, or cyclic alkyl, and the parenthesis represents the presence or absence of hydroxyl, and
• wherein R3 and R4 are independently selected from H, hydroxy, C1-4 alkyl, hydroxy-C1-4alkyl, cyano, cyanoalkyl, nitro, nitroalkyl, —C(O)-aryl, —C(O)H, alkyl aldehyde, carboxyl, and carboxyalkyl, or wherein
• R3 and R4 form a ring of from 4 to 8 member atoms, wherein the ring is substituted with cyano or hydroxy.

A compound according to formula (vii):

• and stereoisomers and salts thereof;
• wherein
• R7 and R8 are independently H, C1-5 alkyl, amino, hydroxyl, cyano, amido, cyclic C3-8 alkyl, or heterocyclyl.

A compound selected from the group consisting of

• and stereoisomers and pharmaceutically acceptable salts thereof.