System and method for prediction of medical treatment effect

A system for use during treatment of an individual having a certain disease and undergoing treatment under a specific line of treatment for the certain disease, the system comprising:

• a data input utility configured and operable to receive medical input data of the individual, the medical input data comprising measured data of one or more medical parameters, the measured data of each one of the one or more medical parameters comprises two or more measured values of the medical parameter being measured at two or more respective time points, said two or more measured values of the medical parameter comprising at least one in-treatment measured value of the at least one medical parameter being measured since onset of the treatment under the specific line of treatment;
• a data processing utility configured and operable for utilizing said medical input data of the individual and processing a disease-specific progression model, corresponding to the certain disease, and determining from said measured data of the one or more medical parameters one or more disease stage indicator values, and processing the one or more disease stage indicator values to generate output data indicative of disease progression occurring within a predetermined treatment period under the specific line of treatment;
• and
• a data output utility configured and operable for outputting said output data, thereby enabling a user of the system to perform one of the following (i) continue with the same treatment under the specific line of treatment (ii) update the treatment under the specific line of treatment, (iii) switch to treatment under a next line of treatment, or (iv) invite the individual for an early disease state assessment.