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AssigneeInstitute of Medical Support Technology, Academy of System Engineering, Academy of Military Science
InventorsJing GUAN, Jian YANG, Ying ZHANG, Feng TIAN, Jimin WU, Sheng DING, Zhihong LI, Chunlai WANG
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The present invention relates to an alkyl chitosan-graphene oxide composite sponge and preparation method and application thereof. The alkyl chitosan-graphene oxide composite sponge provided by the present invention includes alkyl chitosan and graphene oxide absorbed on the alkyl chitosan, and the adsorbing capacity of the graphene oxide is 3-28 wt. %. In the present invention, alkyl chitosan is used as a matrix to combine graphene oxide and alkyl chitosan; the obtained composite sponge has excellent hemostatic performance and blood absorption capacity. Results of embodiments indicate that the in-vitro whole blood coagulation time is less than 58 s, the hemostasis time of a rabbit femoral artery hemorrhage model is less than 155 s, the hemorrhage mass is less than 5.4 g, and the hemostatic effect is superior to a pure alkyl chitosan sponge or graphene oxide powder when the composite sponge provided by the present invention is used for hemostasis.
An alkyl chitosan-graphene oxide composite sponge, comprising alkyl chitosan and graphene oxide absorbed on the alkyl chitosan, wherein the adsorbing capacity of the graphene oxide is 3-28 wt. %.
Dependencies are inferred from the claim text.