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US 2020/0308609 A1Published application
Process for the biological production of methacrylic acid and derivatives thereof
AssigneeLucite International UK Limited
InventorsGraham Ronald EASTHAM, Gill STEPHENS, Andrew Yiakoumetti
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Abstract
A process of producing methacrylic acid and/or derivatives thereof including the following steps: (a) biologically converting isobutyryl-CoA into methacrylyl-CoA by the action of an oxidase; and (b) converting methacrylyl-CoA into methacrylic acid and/or derivatives thereof. The invention also extends to microorganisms adapted to conduct the steps of the process.
Claims23
A process of producing methacrylic acid and/or derivatives thereof comprising the following steps:
- (a) biologically converting isobutyryl-CoA into methacrylyl-CoA by the action of a peroxisomal acyl-CoA oxidase from Vigna radiata;
- and
- (b) converting methacrylyl-CoA into methacrylic acid and/or derivatives thereof.
A microorganism adapted to conduct the following steps:
- (a) biologically converting isobutyryl-CoA into methacrylyl-CoA by expression of a peroxisomal acyl-CoA oxidase from Vigna radiata;
- and
- (b) biologically converting methacrylyl-CoA into methacrylic acid and/or derivatives thereof.
Dependencies are inferred from the claim text.