Method and kit for predicting therapeutic effectiveness of chemotherapy for diffuse large b-cell lymphoma patients
AssigneeKyushu University, National University Corporation
InventorsKohta Miyawaki, Koichi Akashi, Takahiro Maeda, Koji Kato
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Abstract
A method is provided for predicting the therapeutic effectiveness of chemotherapy for a diffuse large B-cell lymphoma patient, including: at least one step selected from the group consisting of a step of measuring expression of a marker of a T cell in a sample obtained from the patient, a step of measuring expression of a marker of a macrophage or a dendritic cell in a sample obtained from the patient, and a step of measuring expression of a marker of a stromal cell in a sample obtained from the patient; and a step of predicting prognosis of the treatment, based on the expression of the marker.
Claims17
A method for predicting therapeutic effectiveness of chemotherapy for a diffuse large B-cell lymphoma patient, comprising:
- at least one step selected from the group consisting of a step of measuring expression of a marker of a T cell in a sample obtained from the patient, a step of measuring expression of a marker of a macrophage or a dendritic cell in a sample obtained from the patient, and a step of measuring expression of a marker of a stromal cell in a sample obtained from the patient;
- and
- a step of predicting probability of progression-free survival (PFS) or probability of overall survival (OS) of the treatment, based on the expression of the marker.
A kit for predicting therapeutic effectiveness of chemotherapy for a diffuse large B-cell lymphoma patient, comprising:
- at least one reagent selected from the group consisting of a reagent for measuring expression of a marker of a T cell, a reagent for measuring expression of a marker of a macrophage or a dendritic cell, and a reagent for measuring expression of a marker of a stromal cell.
Dependencies are inferred from the claim text.