Adeno-associated viral (AAV) vectors useful for transducing adipose tissue
AssigneeUniversitat Autonoma De Barcelona
InventorsVerónica Jiménez Cenzano, Fàtima Bosch Tubert
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Abstract
The present invention relates to adeno-associated viral vector useful for transducing adipose tissue. The invention also relates to polynucleotides, plasmids, vectors and methods for the production of such adeno-associated viral vector. The invention also relates to gene therapy methods useful for the treatment of a disease that requires the regulation of the expression levels of a gene.
Claims20
A method for treating and/or preventing a disease which requires the expression of a polynucleotide of interest in the adipose tissue comprising an adeno-associated viral vector (AAV) comprising a recombinant viral genome wherein said recombinant viral genome comprises an expression cassette, said expression cassette comprising an adipose tissue-specific transcriptional regulatory region operatively linked to a polynucleotide of interest.
Dependencies are inferred from the claim text.