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US 2020/0270213 A1Published application
Entinostat-containing compound, crystal form of compound thereof, and preparation method therefor and pharmaceutical composition thereof
AssigneeHangzhou SoliPharma Co., Ltd.
InventorsXiaohong SHENG, Xiaoxia SHENG
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Abstract
The present invention relates to a compound formed by entinostat as shown in formula (I) and acidic counterion. Compared with the known solid form of entinostat, the compound involved has advantages in terms of solubility, stability, etc. The present invention also relates to a crystalline form of the compound and a preparation method therefor, a pharmaceutical composition thereof and the use thereof in the preparation of a drug for preventing and/or treating a disease associated with differentiation or proliferation.
Claims19
Compound A of formula (II):
Compound B of formula (III):
Dependencies are inferred from the claim text.