US 2020/0270202 A1 · POTENT INHIBITORS OF ASPARTATE N-ACETYL-TRANSFERASE FOR THE TREATMENT OF CANAVAN DISEASE

Abstract

Compounds, compositions, and methods for the treatment of Canavan disease are described.

Dependent claims

A compound comprising Formula I or Formula II:

wherein
n is either 0 or an integer from 1 to 3, and
R is a substituted or unsubstituted aryl, aralkyl, alkoxy, or aryloxy;
and salts, stereoisomers, prodrugs, racemates, solvates, hydrates, and polymorphs thereof.

1 more element

Dependencies are inferred from the claim text.

Facts

Application

16/088,248Filed 23 Mar 2017

Priority

28 Mar 2016

Published

27 Aug 2020

Term ends

Not estimatedThe source records don’t support an estimate.

C07C 233/51
With the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom: having the carbon atom of…
C07C 229/36
The carbon skeleton containing six-membered aromatic rings: with at least one amino group and one carboxyl group bound to the same carbon atom of…
C07C 269/06
Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups [IMAGE cpc-sch-C07C-0964.gif], the nitrogen atom not…: by…
C07C 271/22
With the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms: to carbon atoms of hydrocarbon radicals…

Compounds, compositions, and methods for the treatment of Canavan disease are described.

Dependent claims

A compound comprising Formula I or Formula II:

wherein
n is either 0 or an integer from 1 to 3, and
R is a substituted or unsubstituted aryl, aralkyl, alkoxy, or aryloxy;
and salts, stereoisomers, prodrugs, racemates, solvates, hydrates, and polymorphs thereof.

1 more element

Dependencies are inferred from the claim text.