Method for Processing Solutions of Biomolecules
AssigneeFujifilm Diosynth Biotechnologies UK Limited
InventorsCharles Heise, Tibor Nagy
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Abstract
Apparatus for in-line liquid exchanging a biomolecule-containing liquid is provided. The apparatus comprises a means for mixing at least two liquids comprising a multiple inlet flow-controller, the means for mixing also comprising an outlet in fluid connection with a tangential flow filtration device configured in single-pass mode.
Claims16
Apparatus for in-line liquid exchanging a biomolecule-containing liquid comprising a means for mixing comprising a multiple inlet flow-controller further comprising two or more variable flow inlet valves for mixing at least two liquids, the means for mixing also comprising an outlet in fluid connection with a tangential flow filtration device configured in single-pass mode.
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Apparatus for liquid exchanging a biomolecule-containing liquid comprising:
- a) a multiple inlet flow-controller comprising:
- i) a first inlet for a first liquid medium comprising a biomolecule;
- ii) at least a second inlet for a second liquid medium;
- iii) an outlet in fluid connection with a tangential flow filtration device;
- and
- b) a means for imparting flow of the liquids through the flow-controller and the tangential flow filtration device.
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Dependencies are inferred from the claim text.