Enhancing tissue mechanical properties
AssigneeUniversity of Rochester
InventorCatherine K. Kuo
Life of this patent
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Abstract
The present invention relates to enhancing mechanical properties of tissue such as collagenous or collagen-containing or elastin-containing tissue (e.g., tendons, ligaments, and cartilage) and treating related musculoskeletal and non-musculoskeletal conditions or injuries.
Claims22
A method for (i) improving a mechanical property of a tissue or a component thereof or (ii) regenerating an injured or diseased tissue or developing embryonic/fetal tissue or a component thereof in a subject or (iii) enhance mechanical properties of a healthy tissue, comprising applying a mechanical stimulation to the tissue or cells therein.
A method for (i) improving a mechanical property of a tissue or a component thereof or (ii) regenerating an injured tissue, a diseased or developing embryonic/fetal tissue, or a component thereof in a subject, comprising increasing a level of LOX activity in the tissue.
A pharmaceutical composition comprising (i) a LOX/LOXL enhancer, and (ii) a pharmaceutically acceptable carrier or excipient.
A kit comprising a LOX/LOXL enhancer and a packaging material.
Dependencies are inferred from the claim text.