Compositions and Methods for Treating Cancer
AssigneeTexas Tech University System
InventorsSanjay K. Srivastava, Sharavan Ramachandran
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Abstract
The present invention includes composition and methods for treating cancers comprising administering to a subject a pharmaceutical composition comprising Pimavanserin or derivatives thereof in an amount sufficient to treat the reproductive cancer in the subject and a pharmaceutically acceptable carrier.
Claims44
A method of treating a cancer comprising administering to a subject a pharmaceutical composition comprising Pimavanserin, active polymorphs, analogs, or salts thereof in an amount sufficient to treat the cancer in the subject and a pharmaceutically acceptable carrier.
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A composition for treating a cancer comprising administering to a subject a pharmaceutical composition comprising Pimavanserin, active polymorphs, analogs, or salts thereof provided in in an amount sufficient to treat the cancer in the subject and a pharmaceutically acceptable carrier.
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A method of treating a pancreatic, skin, colon, breast, liver, oesophageal, breast, head and neck, lung, ovarian, renal cell carcinoma, colorectal, glioblastoma, neuroblastoma, medulloblastoma, astrocytoma, brain stem glioma, or brain tumors comprising administering to a subject a pharmaceutical composition comprising Pimavanserin, active polymorphs, analogs, or salts thereof in an amount sufficient to treat the reproductive cancer in the subject and a pharmaceutically acceptable carrier.
A method of evaluating a Pimavanserin, active polymorphs, analogs, or salts thereof believed to be useful in treating a cancer, the method comprising:
- administering the Pimavanserin, active polymorphs, analogs, or salts thereof to a first subset of cancer cells, and a placebo to a second subset of cancer cells;
- and determining if the Pimavanserin, active polymorphs, analogs, or salts thereof reduces the number of cancer cells that is statistically significant as compared to any reduction occurring in the second subset of cancer cells, wherein a statistically significant reduction indicates that the Pimavanserin, active polymorphs, analogs, or salts thereof is useful in treating that cancer.
Dependencies are inferred from the claim text.