Small molecules against cancer
AssigneeBiokine Therapeutics Ltd.
InventorsAmnon PELED, Michal ABRAHAM KARNI, Orly EIZENBERG
Life of this patent
Estimating the term…
Abstract
Compounds capable of, or usable in, killing cancer cells, and/or modulating a biological activity of a chemokine, and/or inhibiting a kinase, and/or treating diseases and disorders associated with a biological activity of a chemokine and/or cell migration, and/or treating disease and disorders such as cancer and inflammatory diseases and disorders, are provided herein. The compounds are listed in Tables 2, 4 and 5, and/or are represented by Formulae I, IV, V and VI, as defined in the specification. Methods utilizing these compounds are also provided.
Claims11
A method of modulating a biological activity of a chemokine in a subject in need thereof, the method comprising administering to the subject a compound having the formula:
- thereby modulating the biological activity of the chemokine,
- wherein said chemokine is selected from MCP-1 and SDF-1.
A method of treating an ocular disease in a subject in need thereof, the method comprising administering to the subject a compound represented by the Formula:
- thereby treating the ocular disease.
Dependencies are inferred from the claim text.