Self-Retaining Implantable Drug Delivery Device
AssigneeGoldenBiotech, LLC
InventorsMerrill Goldenberg, Steven H. Rauchman
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Abstract
Disclosed herein is a medical device for extended release of drugs. The device comprises a stent embedded with one or more drug depots that release of a therapeutic agent in a controlled manner. Each end of the stent may contain one or more anchors or attachment points which enable self-retention of the medical device once properly placed. The disclosed device further comprises a biosensor to monitor physiological characteristics like, e.g., intraocular pressure (IOP).
Claims21
A self-retaining implantable drug delivery device comprising:
- a tubing made of medical grade silicone which forms a semi-rigid cylindrical tube having
- a) a stent portion having a first distal end, a second distal end, and an elongated body between the first distal end and the second distal end;
- and
- b) one or more drug depots including one or more therapeutic agents;
- and
- c) one or more anchors and/or one or more attachment points
A controlled-release drug depot comprising:
- a) a polymer matrix comprising one or more therapeutic drugs;
- and b) a coating layer on an outer surface of the polymer matrix, the polymer layer optionally having openings;
- wherein the one or more therapeutic drugs are released over period of time of at least one week and wherein the release rate approximates zero order kinetics.
A controlled-release drug depot comprising:
- a) a polymer matrix comprising one or more therapeutic drugs;
- and b) a coating layer on an outer surface of the polymer matrix, the polymer layer optionally having openings;
- wherein the one or more therapeutic drugs are released over period of time of at least one week and wherein the release rate approximates zero order kinetics.
Dependencies are inferred from the claim text.