Prosthesis for transcatheter delivery having an infolding longitudinal segment for a smaller radially compressed profile

A heart valve prosthesis having a radially expanded configuration and a radially compressed configuration, the heart valve prosthesis comprising:

• a valve frame including an infolding longitudinal segment, wherein the infolding longitudinal segment of the valve frame extends an entire length of the valve frame and is configured to fold radially inward when the prosthesis is in the radially compressed configuration such that a series of longitudinally aligned apices of the infolding longitudinal segment is disposed radially inward of the remainder of the prosthesis;
• an anchoring frame surrounding and coupled to the valve frame, the anchoring frame including an infolding longitudinal segment that extends an entire length of the anchoring frame and is configured to fold radially inward when the prosthesis is in the radially compressed configuration such that a series of longitudinally aligned apices of the infolding longitudinal segment is disposed radially inward of the remainder of the prosthesis;
• a prosthetic valve component coupled to the valve frame;
• and
• a graft material coupled to at least one of the valve frame and the anchoring frame,
• wherein the infolding longitudinal segment of the anchoring frame is radially aligned with the infolding longitudinal segment of the valve frame.