Method for detecting prostate cancer
AssigneesJ-Oil Mills, Inc., Osaka University
InventorsKazutoshi FUJITA, Norio NONOMURA, Eiji MIYOSHI, Yuka KOBAYASHI
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Abstract
[Problem] To provide a method for detecting prostate cancer, the method having a higher degree of certainty than the PSA blood test and providing measurement values that correlate with risk classification. [Solution] This method for detecting prostate cancer is characterized in that: the method includes reacting fucose α1→6 specific lectin and fucosylated PSA contained in a sample constituted of serum collected from a subject, and detecting the reacted lectin; and the pH in at least one step of the group consisting of the reaction step for reacting the fucosylated PSA and the lectin and processing steps thereafter is adjusted to above 8.5 and less than 11.0.
Claims12
A method for detecting prostate cancer, comprising reacting a fucosylated PSA contained in a specimen consisting of serum sampled from a subject with a fucose α1→6 specific lectin to detect the reacted lectin, wherein
- a pH is adjusted within an alkaline region lower than 11.0 in at least one step of the group consisting of a step for reacting the fucosylated PSA with the lectin and subsequent processing steps.
A diagnostic agent kit for detecting prostate cancer, containing:
- a fucose α1→6 specific lectin;
- and
- an alkaline reagent for adjusting a pH within an alkaline region lower than 11.0 in at least one step selected from a group of steps including a step for reacting a fucosylated PSA contained in a specimen consisting of serum sampled from a subject with the fucose α1→6 specific lectin and subsequent processing steps.
Dependencies are inferred from the claim text.