Early Detection of Colorectal Cancer
AssigneeUniversity of South Carolina
InventorsCAROLE A. OSKERITZIAN, Franklin Berger, Alena P. Chumanevich, John W. Fuseler, Nabihah I. Kumte, Ahmed Aladhami
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Abstract
Methods and systems for detection of precancerous colorectal cancerous lesions and early stage colorectal cancer are described. The methods and systems include examination of a rectal cell sample for the presence of mast cells in a field effect detection regime. The methods can incorporate swab-based cell collection, optionally storage and transportation of a cell sample, and/or computer-aided diagnosis.
Claims16
A method for detection of colorectal cancer or precancerous colon polyps, the method comprising:
- collecting a cell sample from a rectal area of a subject;
- staining the cell sample;
- and
- examining the stained cell sample for the presence or quantity of mast cells;
- wherein
- the presence of mast cells in the cell sample indicates precancerous polyps or colorectal cancer in the colon of the subject.
A system for detection of colorectal cancer or precancerous colon polyps, the system comprising:
- a rectal swab;
- a buffer configured to retain cells collected by the rectal swab;
- a container configured to carry the buffer and cell collected by the rectal swab;
- a cap configured to seal the container.
Dependencies are inferred from the claim text.