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US 2020/0264174 A1Published application
Compounds, complexes, and methods useful for detecting and/or treating bacterial pathogens
AssigneeRegents of the University of Minnesota
InventorsValerie Christine PIERRE, Sylvie PAILLOUX
Life of this patent
Estimating the term…
Abstract
Compounds and complexes that can be useful as enterobactin probes not necessary are disclosed herein. Methods of detecting bacteria and/or methods of determining susceptibility of bacteria to an antibiotic using such compounds and complexes are also disclosed herein.
Claims21
1-32. (Canceled)
A compound selected from one of formula I, II or III:
- wherein:
- each X independently represents H and the vicinal Y represents H or -L-B;
- or each Y independently represents H and the vicinal X represents H or -L-B;
- each Z independently represents H or -L-B;
- each L independently represents an organic linking group;
- each B independently represents —OR, —NR2, —SR, —C(O)OR, —C(O)NR2, —S(O)R, or —SO2R;
- each R independently represents H or an organic group;
- each b is independently 0 or 1;
- each c is independently 0 or 1;
- and
- x=0 to 3;
- with the proviso that at least one of X, Y, or Z is present and represents -L-B;
- wherein:
- each Q independently represents H or —(CH2)n-D, wherein n is 1 to 8;
- each D independently represents —OR, —NR2, —SR, or —C(O)OR;
- each R independently represents H or an organic group;
- and
- each d is independently 2 to 5;
- with the proviso that at least one Q represents —(CH2)n -D;
- and
- wherein:
- each A independently represents —OR, —NR2, —SR, or —C(O)OR;
- each R independently represents H or an organic group;
- each n is independently 2 to 5;
- each e is independently 0 or 1;
- each f is independently 2 or 3;
- each g is independently 0 or 1;
- and
- x=0 to 3;
- with the proviso that at least one A is present.
27 more elements
Dependencies are inferred from the claim text.