Methods and devices for the separation, detection and measurement of molecules in liquid samples
AssigneeGroupe E.N. Biomédical Inc.
InventorElena HAIDET
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Abstract
The invention relates to the field of microfluidic detection and analyses. Described herein are methods and devices for the separation, detection and measurement of molecules in liquid samples. Certain aspects of the invention concerns the separation of analyte(s) of interest based on the combined use of: (i) membrane separation, (ii) an electric field and/or a magnetic field; and (iii) capillary action and/or gravity. Envisioned applications include separation, detection and/or measurement of analytes in blood samples, food samples and environmental samples. One particular example is a portable biosensor for the detection and measurement of histamine and diamine oxidase (DOA) in a drop of blood.
Claims15
-33. (canceled)
A device for the detection of at least one analyte in a liquid sample, comprising:
- a separation zone for depositing a liquid sample comprising at least one analyte to be detected and other constituents, wherein said at least one analyte has a greater size and a charge different from other constituents in the liquid sample;
- a reaction zone for receiving and reacting said at least one analyte;
- a neutral zone in between the separation zone and the reaction zone, the neutral zone allowing flow said at least one analyte from the separation zone to the reaction zone;
- wherein said at least one analyte is detected at the reaction zone by at least one of amperometry, potentiometry, colorimetry and photometry.
-65. (canceled)
Dependencies are inferred from the claim text.