Recombinant vector comprising bip fragment and preparation method of recombinant proteins using thereof
AssigneeBioapplications Inc.
InventorYongjik LEE
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Abstract
Provided is a recombinant vector including a new BiP gene fragment, and when a target protein is prepared using the recombinant vector of the subject matter, use stability can be enhanced and the production amount of target protein can also be increased by minimizing a foreign peptide sequence remaining in the target protein.
Claims23
A gene construct in which a chaperone binding protein (BiP) gene fragment represented by SEQ ID No. 6 and a polynucleotide encoding a target protein are sequentially linked so as to be operable.
A recombinant vector comprising a gene construct in which a promoter gene, a BiP gene fragment represented by SEQ ID No. 6, and a polynucleotide encoding a target protein are sequentially linked so as to be operable.
A recombinant protein in which a BiP fragment represented by SEQ ID No. 7, a linker sequence, and a target protein are sequentially linked.
Dependencies are inferred from the claim text.