Pharmaceutical composition for preventing and treating cancer, containing malate-aspartate shuttle inhibitor and anticancer drug as active ingredients
AssigneeNational Cancer Center
InventorSoo Youl KIM
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Abstract
The present invention relates to a technology for using a malate-aspartate shuttle (MAS) inhibitor as an agent for treating cancer. More particularly, provided is a pharmaceutical composition for preventing or treating cancer, containing, as an active ingredient, phenyl succinic acid, methyl malonic acid, N-(1-pyrenyl)maleimide and phthalonic acid, which are MAS inhibitors, or a mixture of the MAS inhibitor and an anticancer drug.
Claims16
A pharmaceutical composition, comprising a malate-aspartate shuttle (MAS) inhibitor as an active ingredient.
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A method of treating cancer, the method comprising administering an effective amount of a malate-aspartate shuttle inhibitor to an individual in need thereof.
A method of treating cancer, the method comprising administering effective amounts of an MAS inhibitor and an anticancer agent to an individual in need thereof.
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Dependencies are inferred from the claim text.