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US 2020/0263141 A1Published application
Multi-Chimeric Cell and Therapy for Transplantation and Treatment of Immune Deficiencies and Genetic Disorders
AssigneeThe Board of Trustees of the University of Illinois
InventorMaria Siemionow
Life of this patent
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Abstract
A multi-chimeric cell created by ex vivo fusion of three or more hematopoietic stem cells, mesenchymal stem cells, myoblasts, pericytes, or satellite cells, or a combination thereof, from three or more different donors is provided, as is the use of these cells in transplant therapy and treatment of immune deficiency and genetic disorders.
Claims20
A multi-chimeric cell comprising an ex vivo fusion of three or more hematopoietic stem cells, mesenchymal stem cells, myoblasts, pericytes, satellite cells, or a combination thereof, from three or more different donors.
A kit comprising
- (a) a fusogenic agent, and
- (b) three or more donor cells selected from the group of hematopoietic stem cells, mesenchymal stem cells, myoblasts, pericytes, satellite cells, from three or more different donors.
Dependencies are inferred from the claim text.