ANTI-N3pGlu AMYLOID BETA PEPTIDE ANTIBODIES AND USES THEREOF
AssigneeEli Lilly and Company
InventorsRonald Bradley Demattos, Jirong Lu, Ying Tang
Life of this patent
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Abstract
Antibodies to human N3pGlu Aβ, compositions comprising such N3pGlu Aβ antibodies, and methods of using such N3pGlu Aβ antibodies for the treatment of a disease characterized by deposition of Aβ including clinical or pre-clinical Alzheimer's disease, Down's syndrome, and clinical or pre-clinical cerebral amyloid angiopathy.
Claims10
1-25. (canceled)
A DNA molecule comprising a polynucleotide that encodes an antibody heavy chain comprising an amino acid sequence given by SEQ ID NO:12.
A DNA molecule comprising a polynucleotide that encodes an antibody light chain comprising an amino acid sequence given by SEQ ID NO:13.
A DNA molecule comprising a polynucleotide sequence that encodes an antibody heavy chain comprising an amino acid sequence given by SEQ ID NO:
- 12 and a polynucleotide sequence that encodes an antibody light chain comprising an amino acid sequence given by SEQ ID NO:
- 13.
Dependencies are inferred from the claim text.