Method for treatment of moderate to severe erythema symptoms in rosacea patients
AssigneeSol-Gel Technologies Ltd.
InventorsOfer TOLEDANO, Ofra LEVY-HACHAM, Ori NOV, Vered RAM
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AssigneeSol-Gel Technologies Ltd.
InventorsOfer TOLEDANO, Ofra LEVY-HACHAM, Ori NOV, Vered RAM
Estimating the term…
A regimen for the therapeutic treatment of moderate to severe erythema symptoms in rosacea patients, the regimen comprising topically applying to the skin of a subject in need of said treatment a pharmaceutical composition, the pharmaceutical composition comprising about 1% w/w to about 10% w/w benzoyl peroxide as an active ingredient, and a pharmaceutically acceptable carrier or excipient, wherein the benzoyl peroxide is the only active ingredient in said pharmaceutical composition, wherein said pharmaceutical composition is applied once daily for a period of at least about 12 weeks, to achieve a percentage decrease of about 60% in a population exhibiting moderate to severe erythema symptoms when measured at about 12 weeks after initial treatment of the population with the pharmaceutical composition.
A regimen for the therapeutic treatment of moderate to severe erythema symptoms in rosacea patients, the regimen comprising topically applying to the skin of a subject in need of said treatment a pharmaceutical composition, the pharmaceutical composition comprising about 2.5% w/w to about 10% w/w benzoyl peroxide as an active ingredient, and a pharmaceutically acceptable carrier or excipient, wherein the benzoyl peroxide is the only active ingredient in said pharmaceutical composition, wherein said pharmaceutical composition is applied once daily for a period of at least about 12 weeks, to achieve a percentage decrease of about 60% in a population exhibiting moderate to severe erythema symptoms when measured at about 12 weeks after initial treatment of the population with the pharmaceutical composition, and wherein the percentage decrease in the population exhibiting erythema symptoms after treatment with pharmaceutical composition is at least about 10% to about 30% higher than a corresponding decrease in the population exhibiting erythema symptoms after treatment with a vehicle alone.
A regimen for the therapeutic treatment of moderate to severe erythema symptoms in rosacea patients, the regimen comprising topically applying to the skin of a subject in need of said treatment a pharmaceutical composition, the pharmaceutical composition comprising about 2.5% w/w to about 10% w/w benzoyl peroxide as an active ingredient, and a pharmaceutically acceptable carrier or excipient, wherein the benzoyl peroxide is the only active ingredient in said pharmaceutical composition, and wherein after about 2 weeks of treatment with the pharmaceutical composition there is no increase in erythema symptoms.
Dependencies are inferred from the claim text.