Multi-Sensor Intracranial Pressure Monitor For Cerebral Hemodynamic Monitoring
AssigneeThe Regents of the University of Michigan
InventorsKevin R. Ward, Kenn Oldham, Lu Wang, Sardar Ansari
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Abstract
Devices and techniques for continuously monitoring pressure and simultaneously monitoring changes in blood flow, vascular resistance, and/or vascular behavior are provided. The techniques are employed in measuring intracranial pressure (ICP), while simultaneously measuring cerebral blood flow and/or cerebrovascular resistance or behavior. A sensor device includes an optical and piezoelectric sensing assembly integrated into a deployable ICP monitoring device.
Claims18
An insertable catheter apparatus comprising:
- a pressure sensor at a distal end of the catheter and configured to measure first pressure data of a sample region within a subject;
- an optical sensor positioned proximally from the pressure sensor and configured to illuminate an optical sample region and to collect reflected illumination from the optical sample region, the reflected illumination corresponding to blood volume in the optical sample region;
- a piezoelectric pressure sensor positioned adjacent the optical sensor and covering a periphery of the insertable catheter, the piezoelectric pressure sensor configured to measure pressure data for the optical sample region;
- and
- a processing device configured to
- receive the reflected illumination from the optical sensor,
- receive the pressure data from the piezoelectric pressure sensor, and
- analyze the pressure data and reflected illumination, heartbeat-by-heartbeat, and determine (i) vascular resistance over the optical sample region, (ii) a blood flow over optical sample region, and (iii) pressure over the optical sample region.
The insertable catheter of claim 5, wherein the piezoelectric pressure sensor comprises at least one other encapsulating layer covering the piezoelectric layer.
An insertable catheter apparatus comprising:
- a pressure sensor at a distal end of the catheter and configured to measure first pressure data of a sample region within a subject;
- an optical sensor positioned proximally from the pressure sensor and configured to illuminate an optical sample region and to collect reflected illumination from the optical sample region and to determine a differential absorption spectroscopy or to collect scattered illumination from the optical sample region and determine a resonance Raman spectroscopy, the reflected illumination or scattered illumination corresponding to tissue oxygenation and/or mitochondrial function in the optical sample region;
- a piezoelectric pressure sensor positioned adjacent the optical sensor and covering a periphery of the insertable catheter, the piezoelectric pressure sensor configured to measure pressure data for the optical sample region;
- and
- a processing device configured to
- receive reflected illumination data or scattered illumination data from the optical sensor,
- receive the pressure data from the piezoelectric pressure sensor, and
- analyze the pressure data and reflected illumination data or scattered illumination data, heartbeat-by-heartbeat, and determine (i) tissue oxygenation and mitochondrial function over the optical sample region, (ii) a blood flow over optical sample region, and/or (iii) pressure over the optical sample region.
Dependencies are inferred from the claim text.