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US 2020/0225129 A1Published application
Manipulation of microfluidic droplets
AssigneeBio-Rad Laboratories, Inc.
InventorsBenjamin Miller, Brian Hutchison, Andrew Wilson, Jonathan William Larson, Qun Zhong, Yevgeny Yurkovetsky, Darren Roy Link, Mark Weary
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Abstract
The invention provides methods for assessing one or more predetermined characteristics or properties of a microfluidic droplet within a microfluidic channel, and regulating one or more fluid flow rates within that channel to selectively alter the predetermined microdroplet characteristic or property using a feedback control.
Claims12
1-20. (canceled)
A system for controlling droplet flow rate, the system comprising:
- a microfluidic device comprising a microfluidic channel and a merge zone, the microfluidic channel comprising a first stream of droplets and a second stream of droplets;
- a sensor configured to detect flow rates of the first and second streams of droplets in the microfluidic channel;
- and
- a controller operably connected to the sensor, the controller configured to adjust the flow rates relative to each other to cause the first stream of droplets to intercalate with the second stream of droplet in the merge zone.
1 more element
Dependencies are inferred from the claim text.