Compositions and methods for increasing phytochemical bioavailablity and bioactivity
AssigneesNorth Carolina State University, Danmarks Tekniske Universitet
InventorsMia C. Theilmann, Yong Jun Goh, Rodolphe Barrangou, Maher Abou Hachem
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Abstract
The present disclosure relates to the field of microbiota research and therapy. In particular, the present disclosure pro-vides compositions and methods for increasing bioavailability of phytochemicals using probiotic bacteria. Compositions and methods described herein include combinations of probiotic bacteria and prebiotic plant glycosides, wherein the probiotic bacteria are capable of converting the prebiotic plant glycosides into aglycones with increased bioavailability.
Claims26
A composition comprising:
- a probiotic bacterial strain;
- a prebiotic plant glycoside;
- and
- a physiologically acceptable carrier and/or excipient;
- wherein the probiotic bacterial strain is capable of converting e prebiotic plant glycoside into a bioactive aglycone, or derivative thereof.
The composition of claim wherein the probiotic bacterial strain comprises a bacterial species from the genus Lactobacillus.
The composition of claim wherein the probiotic bacterial strain comprises a genetic alteration in one or more genes involved in the phosphotransferase system (PTS).
Dependencies are inferred from the claim text.