Tripartite Androgen Receptor Eliminators, Methods and Uses Thereof
AssigneeSPG Therapeutics, Inc.
InventorZory Shaposhnik
Life of this patent
Estimating the term…
Abstract
The present specification discloses tripartite androgen receptor eliminators (AREs), pharmaceutical compositions and medicaments comprising such AREs, methods and uses for such AREs and compositions and medicaments, and methods and uses for AREs and compositions and medicaments for treating an androgen receptor signaling-mediated condition, disease or disorder.
Claims21
A compound of formula I, wherein ARA is an AR antagonist, L is a linker molecule and EE is an AR elimination promoter or elimination enhancer element.
The pharmaceutical composition according to claim 18, comprising 0.1% to 10% of a compound according to claim 1, 20% to 40% denatured alcohol. 40% to 60% isopropyl myristate, and 10% to 30% Transcutol.
The pharmaceutical composition according to claim 19, comprising 0.5% to 5% of a compound according to claim 1, 25% to 35% denatured alcohol. 45% to 55% isopropyl myristate, and 15% to 25% Transcutol.
21-30. (canceled)
Dependencies are inferred from the claim text.