Quasi-Volumetric Sensing System And Method

A method for quantifying a volume to be reacted in a liquid sample by a chip, wherein the chip comprises a carrier, a plurality of short-range order (SRO) units on the carrier, and a plurality of signal detection units electrically connected to each of the plurality of SRO units, and each of the plurality of SRO units includes a plurality of arrays of protrusions being distributed thereon, the method comprising:

• providing the liquid sample;
• applying the liquid sample on the carrier to enable the plurality of arrays of protrusions to contact a droplet having a specific volume and a first parameter, wherein the droplet originates from the liquid sample;
• detecting the first parameter with a respective one of the plurality of signal detection units;
• and
• calculating the volume to be reacted according to the first parameter and a formula (I) as follows:
• V
• =
• ∑
• i
• =
• 1
• n
• 
• 
• Vi
• 
• (
• θ
• ,
• a
• )
• ,
• (
• I
• )
• where V is the volume to be reacted, Vi is the specific volume, θ is a contact angle formed between the droplet and the surface, a is an area within the first area, and n is the number of the plurality of SRO units.

A quasi-volumetric sensing system for a liquid sample, comprising:

• a carrier including a surface;
• and
• a plurality of short-range order (SRO) units configured on the surface, wherein each of the plurality of SRO units includes a plurality of areas each of which includes a plurality of arrays of protrusions, and a distance between any adjacent two protrusions in one area is different from that in another area,
• wherein the liquid sample is applied to run across the plurality of SRO units to enable at least one droplet from the liquid sample to be retained on at least one of the plurality of arrays of protrusions.