System and Method for Neuromodulation

A neuromodulation system for treating a patient, comprising:

• a therapy device adapted for positioning within a blood vessel;
• a parasympathetic therapy element and a sympathetic therapy element, the therapy device including a distal portion configured to be expandable to an expanded position within the blood vessel, wherein in the expanded position the parasympathetic therapy element and the sympathetic therapy element are positioned in a zone that extends circumferentially from 120 degrees to 240 degrees measured from a mid-anterior point around the circumference of the therapy device;
• and
• a stimulator having a control means with (a) a parasympathetic control function configured to (a) energize the parasympathetic therapy element within the zone in accordance with parasympathetic therapeutic levels selected to capture an efferent parasympathetic nerve fiber that influences heart rate and (b) a sympathetic control function configured to energize the sympathetic therapy element within the zone in accordance with sympathetic therapeutic levels selected to capture an efferent cardiac sympathetic nerve fiber that influences blood pressure, the parasympathetic therapeutic levels and sympathetic therapeutic levels selected to decrease the patient's heart rate and elevate or maintain the blood pressure of the patient during simultaneous operation of the parasympathetic control function and the sympathetic control function.