NS1 Truncated Virus for the Development of Canine Influenza Vaccines
AssigneesUniversity of Rochester, Cornell University
InventorsLuis Martinez-Sobrido, Aitor NOGALES-GONZALEZ, Colin PARRISH
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Abstract
The present invention relates to compositions and methods for the treatment and prevention of canine influenza virus (CIV) and CIV-related pathology. The present invention is based on the development of mutant CIV, having one or more mutations in segment 8, which induces a CIV-specific immune response in a subject.
Claims19
An immunological composition comprising a canine influenza virus (CIV), wherein the CIV comprises one or more mutations in segment 8 of the viral genome.
A method for treating or preventing canine influenza in a subject, the method comprising administering to the subject an immunological composition comprising a canine influenza virus (CIV), wherein the CIV comprises one or more mutations in segment 8 of the viral genome.
Dependencies are inferred from the claim text.