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US 2020/0206149 A1Published application
Inhibition of glutaminase c
AssigneeCornell University
InventorsRichard A. Cerione, Jon W. Erickson, Kristin Wilson Cerione, Jiabin Wang
Life of this patent
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Abstract
The present invention relates to a method of reducing the production of glutamate from glutamine by glutaminase C in a cell or tissue. The method involves inhibiting glutaminase C activity in the cell or tissue under conditions effective to reduce production of glutamate from glutamine. Compounds for carrying out this method are also disclosed.
Claims10
1-10. (canceled)
A method of treating a subject with a condition mediated by production of glutamate from glutamine by glutaminase C, said method comprising:
- selecting a subject with a condition mediated by production of glutamate from glutamine by glutaminase C and
- administering to said selected subject an inhibitor of glutaminase C activity under conditions effective to treat the condition mediated by production of glutamate from glutamine.
15-18. (canceled)
22-30. (canceled)
Dependencies are inferred from the claim text.