Improved production of oxalyl-coa, glyoxylate and/or glycolic acid
AssigneeTeknologian tutkimuskeskus VTT Oy
InventorsMervi Toivari, Marja Ilmén, Merja Penttilä
Life of this patent
Estimating the term…
Abstract
The present invention relates to a method of converting oxalate to oxalyl-coA and/or oxalyl-coA to glyoxylate in a fungus and to a method of producing glycolic acid. Still, the present invention relates to a genetically modified fungus comprising increased enzyme activity associated with oxalyl-CoA. And furthermore, the present invention relates to use of the fungus of the present invention for producing oxalate, oxalyl-coA, glyoxylate and/or glycolic acid from a carbon substrate. Still furthermore, the present invention relates to a method of producing specific products and to a method of preparing the genetically modified fungus of the present invention.
Claims23
A method of producing glycolic acid, said method comprising:
- providing a fungus that has been genetically modified to increase an enzyme activity associated with oxalyl-CoA;
- and
- culturing said fungus in a carbon substrate containing medium to obtain glycolic acid.
A method of converting oxalate to oxalyl-coA and/or oxalyl-coA to glyoxylate in a fungus, said method comprising:
- providing a fungus that has been genetically modified to increase an enzyme activity associated with oxalyl-CoA;
- and
- culturing said fungus in a carbon substrate containing medium to obtain oxalyl-coA and/or glyoxylate.
A genetically modified fungus comprising increased enzyme activity associated with oxalyl-CoA.
(canceled)
(canceled)
Dependencies are inferred from the claim text.