Enriched Cellular Compositions and Therapeutic Use
AssigneeAbraham J and Phyllis Katz Cord Blood Foundation
InventorsMary Laughlin, Jennifer Greene-Roos
Life of this patent
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Abstract
Methods for providing wound healing compositions that include umbilical cord blood derived monocytes and umbilical cord blood derived platelet rich plasma are provided. Methods for treating a non-healing wound in a subject by administration of a wound healing composition that includes umbilical cord blood derived monocytes and umbilical cord blood derived platelet rich plasma are provided.
Claims14
A method for producing a pharmaceutically acceptable wound healing composition for administration to a patient in need thereof comprising:
- producing platelet rich plasma from umbilical cord blood;
- isolating monocytes from umbilical cord blood;
- stimulating the isolated monocytes with deferoxamine in culture in vitro;
- and
- combining the platelet rich plasma and the stimulated monocytes into a pharmaceutically acceptable wound healing composition.
A therapeutic composition for wound healing comprising:
- platelet rich plasma derived from umbilical cord blood;
- and
- monocytes derived from umbilical cord blood,
- wherein the monocytes have been stimulated with deferoxamine in culture in vitro.
A method for treating a non-healing wound in a subject, comprising administering to the subject a composition comprising a therapeutically effective amount of umbilical cord blood derived platelet rich plasma and umbilical cord blood derived monocytes previously stimulated with deferoxamine in culture in vitro.
Dependencies are inferred from the claim text.