Systems and methods for preparing tailored radioactive isotope solutions
AssigneeRadtran LLC
InventorSaleem S. Drera
Life of this patent
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Abstract
The present disclosure relates to systems and methods for producing tailored solutions or medicaments containing radioactive isotopes (e.g., alpha particle emitting radioactive isotopes). The solutions may be produced by appropriate aging and separation steps. Therapeutically effective amounts of Pb-212 and/or Bi-213 may thus be obtained.
Claims12
A method comprising:
- (a) aging a starting actinide element solution comprising Th-232 cations, wherein the aging comprises:
- (i) radioactively decaying at least some of the Th-232 cations, thereby producing an aged starting actinide element solution having at least some progeny divalent cations, wherein the progeny divalent include one or more of Ra-228, Ra-224, Pb-212, and Pb-208;
- and
- (b) flowing the aged starting actinide element solution through a column having an adsorbent, thereby adsorbing, by the adsorbent, at least some of the progeny divalent cations of the aged actinide element solution.
The method of claim 68, comprising generating a Pb-212-containing solution from at least one of (i) the aged extraction effluent solution having Th-228 cations, and (ii) the Ra-224-rich effluent, wherein the Pb-212-containing solution comprises at least some Pb-212 cations.
-20. (canceled)
A method comprising:
- (a) aging a solution having divalent cations therein;
- (i) wherein the divalent cations comprise at least one of Ra-228 cations, Ra-224 cations, Pb-212 cations, and Pb-208 cations;
- and
- (ii) wherein the aging comprises radioactively decaying at least some of the divalent cations, thereby producing an aged solution comprising Ac-228 cations, Th-228 cations, and some of the divalent cations;
- (b) flowing the aged solution through a column comprising an adsorbent, thereby removing at least some of the divalent cations from the aged solution;
- and
- (c) recovering a purified thorium effluent, wherein the purified thorium effluent comprises the aged solution and at least some Th-228 cations.
A method comprising:
- (a) aging a thorium-containing solution;
- (i) wherein the thorium-containing solution comprises at least some Th-228 cations;
- and
- (ii) wherein the aging the thorium-containing solution comprises radioactively decaying at least some of the Th-228 cations, thereby producing an aged solution comprising Ra-224 cations and some Th-228 cations;
- (b) flowing the aged solution through a column comprising an adsorbent, thereby removing at least some of the Ra-224 cations from the aged solution;
- (c) recovering a purified thorium effluent, wherein the purified thorium effluent comprises the aged solution and at least some Th-228 cations.
Dependencies are inferred from the claim text.