Methods and Devices for the Treatment of Food Allergies
AssigneeTexas Tech University System
InventorsHarvinder Singh Gill, Akhilesh Kumar Shakya
Life of this patent
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Abstract
Methods and devices are provided for treating a food allergy in a subject in need thereof. The method entails delivering an effective amount of an allergen associated with the food allergy into the subject's cutis skin layer. Delivering the allergen is carried out by inserting one or more allergen-coated solid microneedles into the subject's skin. The one or more solid microneedles each has a base, shaft and tip, and when inserted in the subject, do not extend beyond the cutis. The allergen is allowed to dissociate from the one or more microneedles while inserted in the subject's cutis. Once the allergen disassociates, the one or more microneedles is removed from the subject's skin.
Claims33
A method for treating a food allergy in a subject in need thereof, comprising,
- delivering an effective amount of an allergen associated with the food allergy into the subject's cutis skin layer, wherein the delivering step is carried out one or more times during an administration period, and comprises,
- (i) inserting one or more solid microneedles each comprising a base, shaft and tip into the subject's skin, wherein at least one microneedle of the one or more solid microneedles does not extend beyond the cutis once inserted, and is coated with an amount of the allergen;
- and
- (ii) allowing the allergen to dissociate from the at least one microneedle while inserted in the subject's cutis;
- and
- (iii) removing the one or more solid microneedles from the subject's skin.
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A microneedle array comprising a plurality of solid microneedles extending from a common substrate, wherein each microneedle of the plurality has a base, shaft and tip, wherein at least one microneedle of the plurality is coated with an effective amount of a food allergen.
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Dependencies are inferred from the claim text.