Cosmetic preservatives as therapeutic corneoscleral tissue cross-linking agents
AssigneeThe Trustees of Columbia University in the City of New York
InventorsDavid Choohyun Paik, Stephen Lewis Trokel
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Abstract
A composition for opththalmic administration comprising a formaldehyde releasing agent, sodium bicarbonate, and an ophthalmically suitable carrier or excipient is provided.
Claims21
1-15. (canceled)
A method of inhibiting loss of structural integrity of a collagenous tissue during transplantation-related transport comprising contacting the collagenous tissue with an amount of a formaldehyde releasing agent effective to inhibit loss of structural integrity of the collagenous tissue.
22-48. (canceled)
A method of altering the refractive power of a cornea comprising contacting the cornea with a formaldehyde releasing agent so as to effect cross-linking in the cornea and thereby alter the refractive power of the cornea.
Dependencies are inferred from the claim text.