Fabp4 as a therapeutic target in skin diseases
AssigneeTicure Ltd.
InventorTali GARIN-SHKOLNIK
Life of this patent
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Abstract
Provided are methods of regulating proliferation and/or differentiation of keratinocytes and immune cells, more specifically to methods of treating pathologies characterized by hyperproliferative keratinocytes or inflammatory skin diseases by administration of FABP4-inhibitor.
Claims32
A pharmaceutical composition comprising at least one FABP4-inhibitor for use in treating or preventing a skin disease.
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A method for treating or preventing a skin disease in a subject, comprising administering to a subject in need thereof, a therapeutically effective amount of at least one FABP4-inhibitor or a pharmaceutical composition comprising thereof.
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A method for detecting the predisposition in a subject for developing a skin disease or condition, comprising:
- detecting expression of FABP4 in a sample containing keratinocytes or inflammatory cells from the subject, wherein the presence of FABP4 in the sample above a pre-determined base-level indicates a predisposition for developing the skin disease or condition.
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Dependencies are inferred from the claim text.