System to manage patient hydration

A patient monitoring device for determining fluid responsiveness of a patient, the patient monitoring device comprising:

• a sensor interface configured to receive a sensor signal from a non-invasive physiological sensor, wherein the non-invasive physiological sensor is configured to emit light towards a tissue site of a patient, detect the light after it has interacted with the tissue site, and generate the sensor signal based at least in part on the detected light;
• and
• a processor in communication with the sensor interface and configured to:
• determine a plethysmograph variability parameter associated with a plethysmograph waveform corresponding to the sensor signal, wherein the plethysmograph waveform comprises a plurality of pulses corresponding to pulsatile blood flow within the tissue site, wherein the plethysmograph variability parameter quantifies variations in the plethysmograph waveform,
• determine a first prediction of fluid responsiveness based at least in part on the plethysmograph variability parameter,
• determine a second prediction of fluid responsiveness based at least in part on a fluid responsiveness parameter that is associated with an elevation of one or more limbs of the patient, and
• output an indication of fluid responsiveness of the patient based at least in part on the first prediction of fluid responsiveness and the second prediction of fluid responsiveness.