Apparatus and method for determining antibiotic resistance using maldi-tof mass spectrometry
AssigneeNosquest Co., Ltd.
InventorsHyung Soon Park, Seong Jin Ahn, Kyoohyoung Rho, Eung Joon Jo
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Abstract
The present invention relates to an apparatus for determining resistance of microorganisms, which may comprise: a storage unit including a database for storing first region mass spectrum data for a plurality of microorganisms and second region mass spectrum data used to determine resistance of each of the plurality of microorganisms; and a processor including a resistance determination module which determines resistance to an antibiotic by comparing the second region mass spectrum data with mass spectrum data of a microorganism sample to be determined.
Claims15
An apparatus for determining a resistance of microorganisms, the apparatus comprising:
- a storage including a database to store first region mass spectrum data associated with a plurality of microorganisms and second region mass spectrum data used for determining a resistance of each of the plurality of microorganisms;
- and
- a processor configured to determine a resistance to an antibiotic by inputting mass spectrum data of a microorganism sample to be determined, to a statistic or machine-learning resistance determining module that determines a resistance using the second region mass spectrum data as input data.
An apparatus for determining a resistance of a microorganism, the apparatus comprising:
- a communicator configured to connect to a cloud server including a database that stores first region mass spectrum data associated with a plurality of microorganisms and second region mass spectrum data used for determining a resistance of each of the plurality of microorganisms;
- and
- a processor configured to determine a resistance to an antibiotic by inputting mass spectrum data of a microorganism sample to be determined, to a statistic or machine-learning resistance determining module that determines a resistance using the second region mass spectrum data as input data.
A method of determining a resistance of a microorganism, the method comprising:
- storing, by a storage, first region mass spectrum data associated with a plurality of microorganisms and second region mass spectrum data used for determining a resistance of each of the plurality of microorganisms in a database;
- and
- determining, by a processor, a resistance to an antibiotic by inputting mass spectrum data of a microorganism sample to be determined, to a statistic or machine-learning resistance determining module that determines a resistance using the second region mass spectrum data as input data.
An operation method of a microorganism resistance determining apparatus, the method comprising:
- acquiring, by a mass analyzer, first region mass spectrum data associated with a microorganism sample to be determined;
- identifying, by a processor, a microorganism by inputting the first region mass spectrum data of the microorganism sample to be determined, to a statistic or machine-learning identifying module that identifies a microorganism using mass spectrum data as input data;
- acquiring, by the mass analyzer, second region mass spectrum data associated with the microorganism sample;
- and
- determining a resistance to an antibiotic by inputting mass spectrum data of the microorganism sample to a statistic or machine-learning resistance determining module that determines a resistance using the first region and second region mass spectrum data as input data.
Dependencies are inferred from the claim text.