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US 2020/0109176 A1Published application
Compositions And Methods For Making And Using Virus-Like Particles (VLPs)
AssigneeUniversity of Massachusetts
InventorTrudy Gilkerson Morrison
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Abstract
The present invention provides compositions and methods for using prophylactic and/or therapeutic vaccines to immunize subjects, and offspring of immunized female subjects, against respiratory syncytial virus (RSV). The invention also provides compositions and methods for producing increased yields of recombinant virus-like particles (VLPs).
Claims12
A vaccine comprising
- a) a recombinant Newcastle disease virus-like particle (ND VLP), said ND VLP comprises recombinant chimeric polypeptide, said recombinant chimeric polypeptide comprising one or more mutation-stabilized pre-fusion F proteins, and
- b) a physiologically acceptable carrier.
Dependencies are inferred from the claim text.