Automated robotic microscopy systems
AssigneeThe J. David Gladstone Institutes
InventorsSteven M. Finkbeiner, Dale Michael Ando, Aaron C. Daub
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Abstract
The present disclosure provides automated robotic microscopy systems that facilitate high throughput and high content analysis of biological samples, such as living cells and/or tissues. In certain aspects, the systems are configured to reduce user intervention relative to existing technologies, and allow for precise return to and re-imaging of the same field (e.g., the same cell) that has been previously imaged. This capability enables experiments and testing of hypotheses that deal with causality over time with greater precision and throughput than conventional microscopy methods.
Claims40
-50. (canceled)
An imaging system the system comprising:
- an imaging device;
- and
- a robotic arm configured to automatically retrieve a sample from a first surface and place the sample on the imaging device,
- wherein the system is configured to automatically identify a fiduciary mark on the sample, move the sample so that the fiduciary mark is in substantially the same position as in a reference image, and acquire an image of the sample.
The system according to claim 51, wherein the robotic arm is configured to automatically retrieve the sample from the imaging device and place the sample on a second surface.
The system according to, wherein the imaging device comprises an inverted microscope body.
-113. (canceled)
Dependencies are inferred from the claim text.